Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | ADH5 | P11766 | 5/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700822 | 0.71 | CYP11B1 (0.42) | CYP11B1CYP11B2PDE3BPDE3ACRBN | |
| SCHEMBL9700811 | 0.65 | PDE3B (0.43) | CYP11B1CYP11B2PDE3BPDE3ACRBN | |
| SCHEMBL16673120 | 0.63 | CYP3A4 (0.62) | CYP11B1CYP11B2ADH5IDO1CYP3A4 | |
| SCHEMBL18288736 | 0.63 | CYP3A4 (0.52) | CYP11B1CYP11B2IDO1CYP3A4BAZ2B | |
| SCHEMBL872411 | 0.63 | LMNA (0.53) | CYP11B1CYP11B2IDO1CYP3A4BAZ2B | |
| SCHEMBL9700837 | 0.62 | PDE3B (0.43) | CYP11B1CYP11B2PDE3BPDE3ACRBN | |
| SCHEMBL12117429 | 0.62 | CYP11B1 (0.56) | CYP11B1CYP11B2PDE3BPDE3AADH5 | |
| SCHEMBL3951714 | 0.62 | KDM4E (0.52) | CYP11B1CYP11B2PDE3BPDE3AADH5 | |
| SCHEMBL5136657 | 0.62 | LMNA (0.49) | CYP11B1CYP11B2PDE3BPDE3AADH5 | |
| SCHEMBL4336106 | 0.60 | CYP11B1 (0.49) | CYP11B1CYP11B2PDE3BPDE3AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | claimed |