Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.38 |
| ▸ | ADH5 | P11766 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700811 | 0.73 | PDE3B (0.43) | CYP11B1CYP11B2PDE3BPDE3ACRBN | |
| SCHEMBL9700819 | 0.71 | CYP11B1 (0.41) | CYP11B1CYP11B2PDE3BPDE3ACRBN | |
| SCHEMBL9700837 | 0.68 | PDE3B (0.43) | CYP11B1CYP11B2PDE3BPDE3ACRBN | |
| SCHEMBL16673120 | 0.64 | CYP3A4 (0.62) | CYP11B1CYP11B2ADH5IDO1 | |
| SCHEMBL18288736 | 0.63 | CYP3A4 (0.52) | CYP11B1CYP11B2IDO1HTT | |
| SCHEMBL872411 | 0.63 | LMNA (0.53) | CYP11B1CYP11B2IDO1HTT | |
| SCHEMBL9699776 | 0.63 | PDE3B (0.38) | CYP11B1CYP11B2PDE3BPDE3ACRBN | |
| SCHEMBL7349312 | 0.63 | PDE3B (0.50) | CYP11B1CYP11B2PDE3BPDE3AIGF1R | |
| SCHEMBL23137976 | 0.63 | PDE3B (0.56) | CYP11B1CYP11B2PDE3BPDE3ACRBN | |
| SCHEMBL12117429 | 0.63 | CYP11B1 (0.56) | CYP11B1CYP11B2PDE3BPDE3AADH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | claimed |