Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.41 |
| ▸ | ELANE | P08246 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30829209 | 0.88 | PREP (0.41) | PREPELANECA12CA1CA9 | |
| SCHEMBL6524959 | 0.85 | MEN1 (0.43) | PREPELANECA12CA1CA9 | |
| SCHEMBL5280416 | 0.85 | ELANE (0.57) | PREPELANEPPARA | |
| SCHEMBL4214241 | 0.82 | ALDH1A1 (0.47) | PREPELANECA12CA1CA9 | |
| SCHEMBL2368966 | 0.81 | PREP (0.45) | PREPCA12CA1CA9L3MBTL1 | |
| SCHEMBL6763899 | 0.79 | PREP (0.53) | PREPCA12CA1CA9HSP90AA1 | |
| SCHEMBL6542930 | 0.79 | CA1 (0.52) | PREPCA12CA1CA9 | |
| SCHEMBL5133427 | 0.79 | PREP (0.43) | PREPELANECA12CA1CA9 | |
| SCHEMBL936407 | 0.79 | MAPT (0.53) | PREPCA12CA1CA9MAPT | |
| SCHEMBL4498801 | 0.79 | PREP (0.43) | PREPELANECA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081191-A | Functionalized polymers prepared by anionic polymerization | THE DOW CHEMICAL COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4975491-A | Functionalized polymers prepared by anionic polymerization | THE DOW CHEMICAL COMPANY (US) | 1990-12-04 | — | — | US | disclosed |