Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2500559 | 0.93 | ELANE (0.52) | ELANEPPARAPREPPPARG | |
| SCHEMBL20364920 | 0.87 | LMNA (0.53) | ELANEALDH1A1SRD5A2PREP | |
| SCHEMBL30829209 | 0.86 | PREP (0.41) | ELANEPREP | |
| SCHEMBL30785086 | 0.86 | STS (0.50) | ELANEALDH1A1STSSRD5A2 | |
| SCHEMBL9700925 | 0.85 | PREP (0.41) | ELANEPPARAPREP | |
| SCHEMBL6542930 | 0.84 | CA1 (0.52) | ALDH1A1SRD5A2PREP | |
| SCHEMBL6524959 | 0.83 | MEN1 (0.43) | ELANEPREP | |
| SCHEMBL7012599 | 0.83 | PREP (0.43) | ELANEALDH1A1SRD5A2PREPPPARG | |
| SCHEMBL9339629 | 0.82 | ELANE (0.61) | ELANEALDH1A1STSGAASRD5A2 | |
| SCHEMBL3550962 | 0.81 | MEN1 (0.49) | ELANEALDH1A1STSGAAPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313560-B1 | CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION | UNIV YALE (US) | 2007-12-19 | — | — | EP | disclosed |
| EP-1313560-A4 | CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION | UNIV YALE (US) | 2005-02-09 | — | — | EP | disclosed |
| EP-1313560-A1 | CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION | YALE UNIVERSITY (US) | 2003-05-28 | — | — | EP | disclosed |
| US-6562989-B2 | Bicyclopentyl iron ligand and transition metal catalyst | YALE UNIVERSITY | 2003-05-13 | — | — | US | disclosed |
| US-20030008768-A1 | Catalyst for aromatic C-O, C-N, and C-C bond formation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | disclosed |
| WO-2002011883-A1 | CATALYST FOR AROMATIC C-O, C-N, and C-C BOND FORMATION | YALE UNIVERSITY (US) | 2002-02-14 | — | — | WO | disclosed |
| US-5264491-A | Block copolymers of styrene-isoprene and aromatic polyesters | EDISON POLYMER INNOVATION CORPORATION (US) | 1993-11-23 | — | — | US | disclosed |
| US-5081191-A | Functionalized polymers prepared by anionic polymerization | THE DOW CHEMICAL COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4975491-A | Functionalized polymers prepared by anionic polymerization | THE DOW CHEMICAL COMPANY (US) | 1990-12-04 | — | — | US | disclosed |