SCHEMBL6524959

SCHEMBL6524959

C=C(c1ccccc1)c1ccc(O[Si](C)(C)C(C)(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PREP P48147 4/20 0.39
ELANE P08246 5/20 0.38
CA12 O43570 4/20 0.38
CA1 P00915 4/20 0.38
CA9 Q16790 4/20 0.38
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25189253 0.93 PREP (0.43) MEN1KMT2APREPELANECA12
SCHEMBL30829209 0.86 PREP (0.41) PREPELANECA12CA1CA9
SCHEMBL2281109 0.85 MEN1 (0.39) MEN1KMT2APREPCA12CA1
SCHEMBL9700925 0.85 PREP (0.41) PREPELANECA12CA1CA9
SCHEMBL5280416 0.83 ELANE (0.57) PREPELANE
SCHEMBL9166260 0.82 MEN1 (0.48) MEN1KMT2AELANECES2CES1
SCHEMBL1070595 0.81 KMT2A (0.39) MEN1KMT2AELANETDP1
SCHEMBL4498801 0.81 PREP (0.43) PREPELANECA12CA1CA9
SCHEMBL4214241 0.81 ALDH1A1 (0.47) PREPELANECA12CA1CA9
SCHEMBL17589894 0.80 MEN1 (0.38) MEN1KMT2AELANEMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4975491-A Functionalized polymers prepared by anionic polymerization THE DOW CHEMICAL COMPANY (US) 1990-12-04 US claimed
US-20050031928-A1 Copolymer and the use of the copolymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-02-10 US disclosed
US-5264491-A Block copolymers of styrene-isoprene and aromatic polyesters EDISON POLYMER INNOVATION CORPORATION (US) 1993-11-23 US disclosed
US-5081191-A Functionalized polymers prepared by anionic polymerization THE DOW CHEMICAL COMPANY (US) 1992-01-14 US disclosed
US-4975491-A Functionalized polymers prepared by anionic polymerization THE DOW CHEMICAL COMPANY (US) 1990-12-04 US disclosed