Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 9/20 | 0.57 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12860025 | 0.86 | FBP1 (0.51) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL20562083 | 0.86 | TSHR (0.47) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL16585371 | 0.86 | FBP1 (0.59) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL5021961 | 0.86 | CYP1A2 (0.47) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL4399378 | 0.85 | RAB9A (0.50) | FBP1TSHRRAB9AMEN1KMT2A | |
| SCHEMBL24901468 | 0.84 | KMT2A (0.43) | FBP1TSHRCYP1A2RAB9AMEN1 | |
| SCHEMBL1549824 | 0.84 | FBP1 (0.58) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL275504 | 0.83 | FBP1 (0.52) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL4681849 | 0.83 | FBP1 (0.55) | FBP1PPARATSHRABCB11CYP1A2 | |
| SCHEMBL7984260 | 0.82 | TSHR (0.64) | FBP1PPARATSHRABCB11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116987-A | METHOD OF PREPARING CHROMAN DERIVATIVES, AND SYNTHESIS INTERMEDIATES | SANOFI (FR) | 1992-05-26 | — | — | US | disclosed |
| US-5071991-A | METHOD OF PREPARING CHROMAN DERIVATIVES, AND SYNTHESIS INTERMEDIATES | SANOFI (FR) | 1991-12-10 | — | — | US | disclosed |