Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24901453 | 0.86 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL24901695 | 0.86 | ALDH1A1 (0.49) | KMT2AMEN1FBP1RAB9AALDH1A1 | |
| SCHEMBL9701146 | 0.84 | FBP1 (0.57) | KMT2AMEN1MAPK1FBP1RAB9A | |
| SCHEMBL15897084 | 0.79 | EPHX2 (0.50) | KMT2AMEN1MAPK1FBP1RAB9A | |
| SCHEMBL2471778 | 0.77 | ALDH1A1 (0.41) | KMT2AMEN1MAPK1ALDH1A1NPSR1 | |
| SCHEMBL15094227 | 0.77 | PIN1 (0.45) | KMT2AMEN1FBP1ALDH1A1NPSR1 | |
| SCHEMBL24901460 | 0.76 | MAPT (0.37) | FBP1ALDH1A1NPSR1POLBLMNA | |
| SCHEMBL24901534 | 0.76 | ALDH1A1 (0.36) | KMT2AMEN1MAPK1FBP1ALDH1A1 | |
| SCHEMBL640891 | 0.74 | SCN5A (0.41) | KMT2AMEN1MAPK1RAB9AALDH1A1 | |
| SCHEMBL29943103 | 0.74 | SCN5A (0.41) | KMT2AMEN1MAPK1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |