Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | DUT | P33316 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2696466 | 0.81 | CYP1A2 (0.41) | HRH3TAAR1DUTKCNH2 | |
| SCHEMBL2821530 | 0.79 | ESR1 (0.45) | ALDH1A1TAAR1LMNA | |
| SCHEMBL2142371 | 0.79 | PPARA (0.42) | HRH3ALDH1A1TSHRDUTGAA | |
| SCHEMBL26807117 | 0.79 | KCNH2 (0.42) | DUTKCNH2 | |
| SCHEMBL1245973 | 0.79 | ELOVL1 (0.41) | TAAR1DUTKCNH2 | |
| SCHEMBL24197444 | 0.79 | TAAR1 (0.44) | ALDH1A1TAAR1 | |
| SCHEMBL2366928 | 0.79 | GFER (0.45) | ALDH1A1TSHRDUT | |
| SCHEMBL5871377 | 0.79 | MEN1 (0.42) | DUT | |
| SCHEMBL21178368 | 0.79 | DUT (0.36) | DUT | |
| SCHEMBL12002587 | 0.79 | CYP3A4 (0.38) | HRH3DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496548-A1 | Carbacyclin analogs | PURDUE RESEARCH FOUNDATION (US) | 1992-07-29 | — | — | EP | disclosed |