Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701310 | 0.81 | HRH3 (0.50) | HRH3HRH4DRD2HTR2AHTR2C | |
| SCHEMBL9728710 | 0.76 | DRD2 (0.40) | HRH3HRH4DRD2DRD3HTR2A | |
| SCHEMBL9701487 | 0.68 | ADRA2A (0.56) | HRH3DRD2HTR1A | |
| SCHEMBL9701550 | 0.68 | ADRA2A (0.60) | HRH3DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL9701405 | 0.67 | ADRA2A (0.62) | HRH3DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL9701449 | 0.67 | DRD2 (0.41) | DRD2DRD3HTR2AHTR2CDRD4 | |
| SCHEMBL9700324 | 0.66 | ADRA2A (0.47) | HRH3DRD2HTR2AHTR2CHRH1 | |
| SCHEMBL9700145 | 0.65 | ADRA2A (0.46) | HRH3DRD2HTR1A | |
| SCHEMBL9700515 | 0.65 | HRH3 (0.47) | HRH3HRH4DRD2HTR2AHTR1A | |
| SCHEMBL9700376 | 0.64 | GAA (0.47) | HRH3HRH4DRD2DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112820-A | Vision defects | STERLING DRUG INC. (US) | 1992-05-12 | — | — | US | disclosed |