Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413251 | 0.88 | PTGDR2 (0.61) | PTGDR2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL9700697 | 0.84 | BRCA1 (0.49) | ALDH1A1KDM4EHSD17B10BRCA1KMT2A | |
| SCHEMBL9701778 | 0.83 | ALDH1A1 (0.45) | PTGDR2ALDH1A1KDM4EHSD17B10BRCA1 | |
| SCHEMBL18402953 | 0.80 | BRCA1 (0.55) | ALDH1A1KDM4EHSD17B10BRCA1KMT2A | |
| SCHEMBL8530610 | 0.75 | KMT2A (0.69) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL8530608 | 0.74 | KMT2A (0.48) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL9703067 | 0.74 | KMT2A (0.48) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL9701525 | 0.74 | ALDH1A1 (0.44) | PTGDR2ALDH1A1KDM4EHSD17B10BRCA1 | |
| SCHEMBL9700688 | 0.74 | BRCA1 (0.44) | PTGDR2ALDH1A1KDM4EHSD17B10BRCA1 | |
| SCHEMBL28555490 | 0.73 | CDC25A (0.51) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132319-A | Antiasthmatic, antiinflammatory, antiallergen and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-21 | — | — | US | disclosed |