Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28313770 | 0.81 | HDAC1 (0.68) | HTR6HDAC1HDAC8HDAC6CYP19A1 | |
| SCHEMBL15705721 | 0.81 | HDAC1 (0.64) | HTR6HDAC1HDAC8HDAC6CYP19A1 | |
| SCHEMBL9701189 | 0.80 | HTR6 (0.58) | HTR6HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL9701185 | 0.80 | HTR6 (0.58) | HTR6HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL9701519 | 0.79 | KMT2A (0.60) | HTR6HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL3328890 | 0.77 | HTR6 (1.00) | HTR6HDAC3 | |
| SCHEMBL28144839 | 0.76 | CYP19A1 (0.58) | HTR6HDAC1HDAC8HDAC6CYP19A1 | |
| SCHEMBL9701531 | 0.75 | CDC25A (0.49) | HTR6POLB | |
| SCHEMBL9701366 | 0.74 | HTR6 (0.62) | HTR6HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL15330109 | 0.73 | ALDH1A1 (0.39) | POLBKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132319-A | Antiasthmatic, antiinflammatory, antiallergen and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-21 | — | — | US | disclosed |