Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 2/20 | 0.42 |
| ▸ | CMA1 | P23946 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 5/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701302 | 0.88 | PTGDR2 (0.45) | AKR1B1AKR1A1TRAP1HSP90B1MEN1 | |
| SCHEMBL9683456 | 0.85 | CTSG (0.42) | CTSGCMA1AKR1B1AKR1A1TRAP1 | |
| SCHEMBL9700055 | 0.74 | TRAP1 (0.48) | AKR1B1AKR1A1TRAP1HSP90B1TBXA2R | |
| SCHEMBL9681415 | 0.74 | PTGDR2 (0.43) | AKR1B1AKR1A1TRAP1HSP90B1TBXA2R | |
| SCHEMBL9701528 | 0.72 | TRAP1 (0.43) | AKR1B1AKR1A1TRAP1HSP90B1MEN1 | |
| SCHEMBL9701300 | 0.68 | TRAP1 (0.41) | AKR1B1AKR1A1TRAP1HSP90B1TBXA2R | |
| SCHEMBL9683001 | 0.66 | CTSG (0.66) | CTSGCMA1MEN1KMT2ATBXA2R | |
| SCHEMBL2818682 | 0.66 | PDPK1 (0.56) | AKR1B1AKR1A1KDM4E | |
| SCHEMBL9699251 | 0.66 | HPGD (0.54) | MEN1KMT2ATBXA2RL3MBTL1MAPT | |
| SCHEMBL9683250 | 0.65 | TBXA2R (0.66) | CTSGCMA1TBXA2RL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |