Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701665 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL11736292 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL11741908 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL7365683 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9524981 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL7397061 | 0.73 | KDM4E (0.64) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| Dimethylamine SCHEMBL9701559 | 0.72 | KDM4E (0.62) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9529307 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9701530 | 0.71 | KDM4E (0.65) | KDM4EALDH1A1GAAL3MBTL1GLA | |
| SCHEMBL9700663 | 0.71 | MAPT (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |