Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GLA | P06280 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | PIM1 | P11309 | 2/20 | 0.61 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701530 | 0.88 | KDM4E (0.65) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9526258 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL7371751 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9701620 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL7371748 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9701626 | 0.80 | ALDH1A1 (0.56) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9526844 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9701927 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9701556 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9524533 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1GLAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |