Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843955 | 0.98 | APLNR (0.51) | TDP1L3MBTL1APLNRCALM1ALOX15 | |
| SCHEMBL1845841 | 0.93 | APLNR (0.53) | TDP1L3MBTL1APLNRCALM1ALOX15 | |
| SCHEMBL1845745 | 0.86 | APLNR (0.56) | TDP1APLNRCALM1ALDH1A1CA12 | |
| SCHEMBL24041808 | 0.84 | APLNR (0.47) | APLNRCALM1ALDH1A1LMNATSHR | |
| SCHEMBL22750781 | 0.83 | L3MBTL1 (0.56) | TDP1L3MBTL1APLNRCALM1ALOX15 | |
| SCHEMBL7597791 | 0.82 | KDM4E (0.50) | TDP1L3MBTL1ALOX15ALDH1A1KDM4E | |
| SCHEMBL26316551 | 0.81 | ALDH1A1 (0.54) | ALOX15ALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL8435356 | 0.81 | KDM4E (0.54) | TDP1L3MBTL1ALOX15ALDH1A1KDM4E | |
| SCHEMBL6041286 | 0.81 | KDM4E (0.54) | TDP1L3MBTL1ALOX15ALDH1A1KDM4E | |
| SCHEMBL23014971 | 0.81 | KDM4E (0.54) | TDP1L3MBTL1ALOX15ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086065-A | Leukotriene antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-02-04 | — | — | US | disclosed |