Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146698 | 0.81 | — | — | |
| Biphenyl SCHEMBL9277907 | 0.80 | MAPT (0.44) | BLMKDM4EGAAAURKAAURKB | |
| Hydrogen Sulfide SCHEMBL27904031 | 0.79 | — | — | |
| Chlorobenzene SCHEMBL27770107 | 0.77 | TSHR (0.42) | CYP1A2CYP2C9CYP2C19BLMKDM4E | |
| SCHEMBL27508884 | 0.72 | MCL1 (0.53) | BLMKDM4EGAAKMT2AAURKA | |
| SCHEMBL9702809 | 0.71 | DAO (0.47) | BLMKDM4EGAAKMT2AAURKA | |
| 4-Phenyl-Butylamine SCHEMBL9702214 | 0.70 | MAOA (0.56) | DAOHPGD | |
| Phenylhydrazine SCHEMBL29066355 | 0.70 | TDP1 (0.88) | IDO1LMNACYP1A2CYP3A4CYP2D6 | |
| Phenylhydrazine SCHEMBL9742536 | 0.70 | TDP1 (0.88) | IDO1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20005911 | 0.69 | TDP1 (1.00) | IDO1LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003732-A2 | COMPOSITIONS AND METHODS FOR ENHANCED BINDING IN BIOLOGICAL ASSAYS | BIOPROBE INTERNATIONAL, INC. (US) | 1992-03-05 | — | — | WO | disclosed |