Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699664 | 0.86 | MMP1 (0.41) | ERBB2NQO2 | |
| SCHEMBL9700956 | 0.83 | TSHR (0.37) | ERBB2NQO2MEN1KMT2AMAPT | |
| SCHEMBL9700960 | 0.81 | MAPT (0.35) | ERBB2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9740990 | 0.81 | MAPT (0.35) | ERBB2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4177978 | 0.79 | ERBB2 (0.61) | ERBB2NQO2MEN1KMT2AMAPT | |
| SCHEMBL9746062 | 0.76 | MMP1 (0.36) | — | |
| SCHEMBL9163760 | 0.73 | TSHR (0.42) | NQO2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9701973 | 0.71 | NQO2 (0.39) | NQO2MAPTKDM4E | |
| SCHEMBL8645097 | 0.71 | KMT2A (0.36) | MEN1KMT2AMAPTKDM4E | |
| SCHEMBL8644084 | 0.71 | KMT2A (0.36) | ERBB2MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5118675-A | Therapy for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |