Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702721 | 0.89 | NPC1 (0.55) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL10870450 | 0.85 | KDM4E (0.48) | MEN1KMT2ANPC1RAB9AATM | |
| Clanfenur SCHEMBL29356092 | 0.83 | RAB9A (0.50) | MEN1KMT2ANPC1RAB9ACNR1 | |
| SCHEMBL9688121 | 0.83 | KMT2A (0.60) | MEN1KMT2ANPC1RAB9AATM | |
| Clanfenur SCHEMBL93573 | 0.83 | RAB9A (0.50) | MEN1KMT2ANPC1RAB9ACNR1 | |
| SCHEMBL9687005 | 0.79 | RXFP1 (0.56) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL11172881 | 0.76 | ATM (0.50) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL11394995 | 0.74 | KDM4E (0.61) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL11404820 | 0.74 | ATM (0.48) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL10713412 | 0.74 | ATM (0.41) | MEN1KMT2ANPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475506-A1 | Pharmaceutical formulation containing a benzoyl urea derivative | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-03-18 | — | — | EP | claimed |
| EP-0475506-A1 | Pharmaceutical formulation containing a benzoyl urea derivative | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-03-18 | — | — | EP | disclosed |