Clanfenur

Clanfenur

SCHEMBL93573

CN(C)c1cccc(F)c1C(=O)NC(=O)Nc1ccc(Cl)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.50
NPC1 O15118 5/20 0.50
GAA P10253 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
MAPT P10636 3/20 0.45
CNR1 P21554 6/20 0.44
TSHR P16473 3/20 0.44
NPSR1 Q6W5P4 3/20 0.44
ALDH1A1 P00352 3/20 0.44
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clanfenur SCHEMBL29356092 1.00 RAB9A (0.50) RAB9ANPC1GAACYP3A4CYP2C9
Diflubenzuron SCHEMBL42416 0.87 RAB9A (0.59) RAB9ANPC1GAAKMT2AMEN1
Diflubenzuron SCHEMBL18837607 0.87 RAB9A (0.59) RAB9ANPC1GAAKMT2AMEN1
SCHEMBL9324631 0.84 RAB9A (0.57) RAB9ANPC1GAAKMT2AMEN1
SCHEMBL9701811 0.83 MEN1 (0.50) RAB9ANPC1GAAKMT2AMEN1
SCHEMBL10711203 0.83 RAB9A (0.56) RAB9ANPC1GAAKMT2AMEN1
Diflubenzuron SCHEMBL8729691 0.83 NPC1 (0.56) RAB9ANPC1GAAKMT2AMEN1
Diflubenzuron SCHEMBL28169066 0.82 NPC1 (0.54) RAB9ANPC1GAAKMT2AMEN1
SCHEMBL9686167 0.82 RAB9A (0.54) RAB9ANPC1GAAKMT2AMEN1
SCHEMBL9688121 0.80 KMT2A (0.60) RAB9ANPC1GAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1073 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3037529-B1 EXTENDED SOLUBLE PH20 POLYPEPTIDES AND USES THEREOF HALOZYME INC (US) 2019-03-27 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
CN-104244968-A PH20 polypeptide variants, formulations, and uses thereof HALOZYME INC 2014-12-24 CN claimed
JP-2011528275-A 2011-11-17 JP claimed
EP-2313122-A1 DRUG DELIVERY MEDICAL DEVICE Micell Technologies, Inc. (US) 2011-04-27 EP claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
WO-2010009335-A1 DRUG DELIVERY MEDICAL DEVICE MICELL TECHNOLOGIES, INC. (US) 2010-01-21 WO claimed
US-20090054369-A1 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS, INC. (US) 2009-02-26 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
EP-1919929-A4 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS INC (US) 2008-08-06 EP claimed
EP-1919929-A2 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND Pharmaceuticals, Inc. (US) 2008-05-14 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2007019221-A2 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS, INC. (US) 2007-02-15 WO claimed
EP-0393575-B1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent SEARLE & CO (US) 1994-03-16 EP claimed
US-5166180-A Administering diphenyl substituted (thio)carbonyl(thio)urea derivatives DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1992-11-24 US claimed
EP-0475506-A1 Pharmaceutical formulation containing a benzoyl urea derivative DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1992-03-18 EP claimed
EP-0393575-A1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent G.D. Searle & Co. (US) 1990-10-24 EP claimed
US-20260014172-A1 ABIRATERONE PRODRUGS ASTELLAS US LLC (US) 2026-01-15 US disclosed
EP-0324521-A2 Method of treating haematologic diseases and pharmaceutical compositions to be used therefor DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1989-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014172-A1 ABIRATERONE PRODRUGS SHBG, CYP17A1, HSD17B11 RAB9A 2864/4885NPC1 930/4885GAA 3528/4885
US-20090054369-A1 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS SI, SLC29A2, SLC29A1 RAB9A 1315/4885NPC1 360/4885GAA 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.