SCHEMBL9701896

SCHEMBL9701896

CC(C)c1cc(Sc2cc(C(C)C)c(O)c(C(C)C)c2)cc(C(C)C)c1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
GABRA1 P14867 6/20 0.56
GABRB1 P18505 5/20 0.56
GABRB2 P47870 3/20 0.56
CYP1A2 P05177 3/20 0.48
CYP3A4 P08684 3/20 0.48
FAAH O00519 1/20 0.48
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
GABRG2 P18507 1/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
HTR2C P28335 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
HTR2B P41595 1/20 0.48
GABRA2 P47869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10893299 0.86 CA1 (0.47) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL10997298 0.85 CA1 (0.61) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL10894340 0.82 CA1 (0.42) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL3132119 0.82 HPN (0.50) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL202336 0.78 CA1 (0.52) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL646501 0.78 HPN (0.55) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL3129487 0.78 TSHR (0.45) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL4676830 0.76 GABRA1 (0.52) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL1760529 0.76 CA1 (0.70) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL275427 0.76 CA1 (1.00) CA1CA2GABRA1GABRB1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4626259-A ADDITIVE OF ORGANIC NITRATE IGNITION ACCELERATOR AND 4,4'-THIOBISPHENOLS; REDUCED COKING OF INJECTOR NOZZLES ETHYL CORPORATION (US) 1986-12-02 US claimed
US-5175372-A Reacting phenol with sulfur dichloride in nonpolar solvent, removing, dissolving in polar solvent, crystallizing SEITETSU KAGAKU CO., LTD. (JP) 1992-12-29 US disclosed
US-5102858-A HEAT-SENSITIVE RECORDING MATERIALS CONTAINING HIGH PURITY BIS(4-HYDROXYPHENYL)SULFIDES SEITETSU KAGAKU CO., LTD. (JP) 1992-04-07 US disclosed
EP-0346824-A2 Process of producing high purity bis(4-hydroxyphenyl) sulfides and heat-sensitive recording materials contaning the same SEITETSU KAGAKU CO., LTD. (JP) 1989-12-20 EP disclosed
US-4626259-A ADDITIVE OF ORGANIC NITRATE IGNITION ACCELERATOR AND 4,4'-THIOBISPHENOLS; REDUCED COKING OF INJECTOR NOZZLES ETHYL CORPORATION (US) 1986-12-02 US disclosed