Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.68 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711975 | 0.97 | LTB4R (0.72) | LTB4RLTB4R2ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL8994890 | 0.96 | LTB4R (0.71) | LTB4RLTB4R2ALDH1A1MAPTLMNA | |
| SCHEMBL8994985 | 0.94 | LTB4R (0.68) | LTB4RLTB4R2ALDH1A1MAPTLMNA | |
| Fumaric Acid SCHEMBL3182319 | 0.93 | LTB4R (0.76) | LTB4RLTB4R2ALDH1A1MAPTLMNA | |
| Maleic Acid SCHEMBL7748813 | 0.93 | LTB4R (0.76) | LTB4RLTB4R2ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL8995021 | 0.93 | LTB4R (0.68) | LTB4RLTB4R2MAPTPLA2G4BPRSS1 | |
| SCHEMBL8994967 | 0.90 | LTB4R (0.63) | LTB4RLTB4R2ALDH1A1MAPTLMNA | |
| SCHEMBL9699613 | 0.88 | LTB4R (0.59) | LTB4RLTB4R2ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL9701722 | 0.87 | LTB4R (0.58) | LTB4RLTB4R2ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL8995013 | 0.86 | LTB4R (0.56) | LTB4RLTB4R2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518819-A2 | Amidino compounds, their manufacture and use as medicament | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | disclosed |