SCHEMBL9702208

SCHEMBL9702208

C[Si](O[Si](C)(c1ccccc1)c1ccc(Oc2ccccc2)cc1)(c1ccccc1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.50
TSHR P16473 1/20 0.50
NR1H2 P55055 1/20 0.45
BAX Q07812 1/20 0.45
MAOA P21397 1/20 0.45
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
TLR8 Q9NR97 1/20 0.41
PGR P06401 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.39
GSTP1 P09211 1/20 0.38
SOS1 Q07889 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433139 0.84 ESR1 (0.42) LTA4HTSHRNR1H2CA1CA2
SCHEMBL19985748 0.83 LTA4H (0.56) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL10945038 0.80 LTA4H (0.57) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL8954924 0.80 LTA4H (0.57) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL10317741 0.79 LTA4H (0.50) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL19985751 0.78 LTA4H (0.48) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL10319647 0.77 LTA4H (0.52) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL31410715 0.77 TSHR (0.42) TSHRMAOAHTTSMN1; SMN2
SCHEMBL3972186 0.75 LTA4H (0.56) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL1929693 0.75 LTA4H (0.56) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4242479-A CATALYST OF ALUMINUM TRIHALIDE, ORGANOSILOXANE COMPOUND OR ETHER, MAGNESIUM ALCOHOLATE, TITANIUM-HALOGEN AND ORGANOALUMINUM COMPOUNDS SHOWA YUKA KABUSHIKI KAISHA (JP) 1980-12-30 US claimed
EP-0490480-A1 Preparation of aluminum oxynitride from organosiloxydihaloalanes FORD MOTOR COMPANY LIMITED (GB) 1992-06-17 EP disclosed
US-5075265-A Preparation of aluminum oxynitride from organosiloxydihaloalanes FORD MOTOR COMPANY (US) 1991-12-24 US disclosed
US-4242479-A CATALYST OF ALUMINUM TRIHALIDE, ORGANOSILOXANE COMPOUND OR ETHER, MAGNESIUM ALCOHOLATE, TITANIUM-HALOGEN AND ORGANOALUMINUM COMPOUNDS SHOWA YUKA KABUSHIKI KAISHA (JP) 1980-12-30 US disclosed
US-4180636-A MAGNESIUM HALIDE, TITANIUM COMPOUND ELECTRON DONOR COMPOUND, TRIALKYL ALUMINUM CATALYST SHOWA DENKO KABUSHIKI KAISHA (JP) 1979-12-25 US disclosed