Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 6/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279235 | 0.85 | PRCP (0.44) | DPP4HRH3FAPDPP8DPP9 | |
| SCHEMBL7284906 | 0.85 | PRCP (0.44) | DPP4HRH3FAPDPP8DPP9 | |
| SCHEMBL7284993 | 0.84 | NPC1 (0.47) | DPP4FAP | |
| SCHEMBL9702219 | 0.84 | DPP4 (0.49) | OPRD1DPP4 | |
| SCHEMBL7271931 | 0.82 | KCNH2 (0.53) | OPRD1DPP4HRH3KCNH2DPP8 | |
| SCHEMBL7278569 | 0.82 | KMT2A (0.49) | DPP4HRH3FAPDPP8DPP9 | |
| SCHEMBL7272234 | 0.81 | CCR1 (0.48) | OPRD1DPP4KCNH2 | |
| SCHEMBL7279739 | 0.79 | UTS2R (0.43) | HRH3PDPK1 | |
| SCHEMBL7279154 | 0.78 | MEN1 (0.54) | DPP4 | |
| SCHEMBL7272151 | 0.77 | MLYCD (0.42) | OPRD1DPP4HRH3KCNH2FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277588-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | claimed |
| EP-0277588-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-08-10 | — | — | EP | claimed |
| US-4977180-A | ANTIAMNESIA AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |