Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952972 | 0.84 | KMT2A (0.51) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2137686 | 0.73 | FDPS (0.49) | NPC1ALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL16767954 | 0.73 | FDPS (0.49) | RAB9ANPC1ALDH1A1HTTPOLB | |
| SCHEMBL1075052 | 0.72 | FDPS (0.51) | RAB9ANPC1ALDH1A1HTTPOLB | |
| SCHEMBL4877813 | 0.72 | FDPS (0.47) | RAB9ANPC1ALDH1A1HTTPOLB | |
| Hydrochloric Acid SCHEMBL9715312 | 0.72 | FDPS (0.47) | NPC1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL28245953 | 0.71 | FDPS (0.44) | NAMPTNPC1ALDH1A1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL8604193 | 0.70 | FDPS (0.46) | RAB9ANPC1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7569658 | 0.70 | NAMPT (0.47) | RAB9ANAMPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7561381 | 0.70 | NOS1 (0.67) | RAB9ANAMPTNPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012154-A1 | IMIDAZOTRIAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-23 | — | — | WO | disclosed |