Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27928023 | 0.82 | PTGS1 (0.48) | PTGS1PTGS2CA1CA2SHBG | |
| SCHEMBL4633834 | 0.79 | PTGS1 (0.50) | PTGS1PTGS2CA1CA2SHBG | |
| SCHEMBL10366947 | 0.78 | PTGS1 (0.46) | PTGS1PTGS2CA1CA2SHBG | |
| SCHEMBL3801816 | 0.78 | PTGS1 (0.68) | PTGS1PTGS2CA1CA2SHBG | |
| SCHEMBL8370720 | 0.76 | PTGS1 (0.47) | PTGS1PTGS2CA1CA2SHBG | |
| SCHEMBL10834423 | 0.74 | PTGS1 (0.46) | PTGS1PTGS2CA1CA2SHBG | |
| SCHEMBL6671173 | 0.74 | PTGS1 (0.46) | PTGS1PTGS2CA1CA2SHBG | |
| SCHEMBL8846095 | 0.73 | PTGS2 (0.57) | PTGS1PTGS2CA1CA2SHBG | |
| SCHEMBL2570939 | 0.73 | PTGS2 (0.57) | PTGS1PTGS2CA1CA2SHBG | |
| SCHEMBL27798205 | 0.72 | PTGS2 (0.47) | PTGS1PTGS2CA1CA2SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120843-A | Nervous system disorders | UPJOHN (US) | 1992-06-09 | — | — | US | disclosed |