Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24796621 | 0.87 | KMT2A (0.55) | MAPK1KMT2ARAB9AMEN1TSHR | |
| SCHEMBL9702659 | 0.85 | MAPK1 (0.61) | MAPK1KMT2ARAB9ANPC1TSHR | |
| SCHEMBL21389186 | 0.84 | KDM4E (0.49) | MAPK1KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL9851181 | 0.84 | KMT2A (0.58) | MAPK1KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL5656878 | 0.83 | RAB9A (0.61) | KMT2ARAB9ANPC1MEN1TSHR | |
| SCHEMBL6359808 | 0.82 | RAB9A (0.60) | MAPK1KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL4160352 | 0.82 | MAPK1 (0.55) | MAPK1KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL21998655 | 0.82 | MAPK1 (0.56) | MAPK1KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL21998656 | 0.82 | MAPK1 (0.56) | MAPK1KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL21999368 | 0.82 | MAPK1 (0.56) | MAPK1KMT2ARAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118811-A | Treatment and prevention of dementia and amnesia | JAPAN TOBACCO INC. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0419683-A1 | NEW AMINO ACID DERIVATIVES HAVING PROLYLENDOPEPTIDASE INHIBITOR ACTIVITY | Japan Tobacco Inc. (JP) | 1991-04-03 | — | — | EP | disclosed |