Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697555 | 0.76 | TAAR1 (0.34) | MAOATAAR1SLC6A2SIGMAR1SLC6A4 | |
| SCHEMBL12814850 | 0.76 | TAAR1 (0.33) | MAOATAAR1SLC6A2SIGMAR1SLC6A4 | |
| SCHEMBL2272014 | 0.73 | TP53 (0.38) | — | |
| SCHEMBL16395648 | 0.73 | TAAR1 (0.33) | MAOATAAR1SLC6A2SIGMAR1SLC6A4 | |
| SCHEMBL273487 | 0.73 | ALDH1A1 (0.33) | MAOATAAR1SLC6A2SIGMAR1SLC6A4 | |
| SCHEMBL2272064 | 0.70 | TP53 (0.35) | — | |
| SCHEMBL15557612 | 0.70 | RIPK1 (0.34) | MAOATAAR1SLC6A2SIGMAR1SLC6A4 | |
| SCHEMBL1314171 | 0.70 | TAAR1 (0.39) | MAOATAAR1SLC6A2SIGMAR1SLC6A4 | |
| SCHEMBL705419 | 0.69 | TDP1 (0.33) | MAOATAAR1SLC6A2SIGMAR1SLC6A4 | |
| SCHEMBL27290628 | 0.69 | LOXL2 (0.38) | MAOATAAR1CYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153343-A | Methyl isopropyl hydrocarbyl halo silane; stability | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 1992-10-06 | — | — | US | claimed |
| CN-103476735-A | Method for producing 1-hexene | SUMITOMO CHEMICAL CO | 2013-12-25 | — | — | CN | disclosed |