Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1918647 | 0.79 | GABRA1 (0.52) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL840750 | 0.77 | GABRA1 (0.64) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28646156 | 0.76 | GABRA1 (0.40) | GABRA1GABRB2TAAR1 | |
| SCHEMBL6114080 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2LMNA | |
| SCHEMBL1314172 | 0.75 | GABRA1 (0.47) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5174943 | 0.74 | GABRA1 (0.61) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5174936 | 0.74 | GABRA1 (0.61) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3481942 | 0.72 | HTR1A (0.36) | TAAR1 | |
| Hydrogen Peroxide SCHEMBL5685702 | 0.72 | GABRA1 (0.65) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL196980 | 0.71 | SLC6A2 (0.53) | GABRA1GABRB2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153343-A | Methyl isopropyl hydrocarbyl halo silane; stability | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 1992-10-06 | — | — | US | claimed |