Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.79 |
| ▸ | APAF1 | O14727 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | THRB | P10828 | 1/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.65 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | USP2 | O75604 | 4/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.65 |
| ▸ | BRD4 | O60885 | 9/20 | 0.59 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437193 | 0.88 | KMT2A (0.78) | MAPTALDH1A1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL5309421 | 0.88 | ALDH1A1 (1.00) | MAPTALDH1A1SMN1; SMN2KDM4EAPAF1 | |
| Hydrochloric Acid SCHEMBL9080389 | 0.87 | ALDH1A1 (0.97) | MAPTALDH1A1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL24211674 | 0.83 | ALDH1A1 (0.66) | MAPTALDH1A1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL9078889 | 0.80 | USP2 (0.76) | MAPTALDH1A1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL3891083 | 0.80 | KMT2A (0.74) | MAPTALDH1A1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL23838880 | 0.79 | KDM4E (0.60) | MAPTALDH1A1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL9437182 | 0.79 | USP2 (1.00) | MAPTALDH1A1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL12023617 | 0.78 | KMT2A (0.70) | MAPTALDH1A1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL7646893 | 0.78 | KMT2A (0.70) | MAPTALDH1A1SMN1; SMN2KDM4EAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005153-A1 | ANTIPROLIFERATIVE SUBSTITUTED NAPHTHALENE COMPOUNDS | AGOURON PHARMACEUTICALS, INC. (US) | 1992-04-02 | — | — | WO | disclosed |