Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 10/20 | 0.47 |
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | HRH1 | P35367 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | HRH2 | P25021 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537572 | 0.79 | DRD3 (0.47) | DRD3DRD2HRH1KCNH2HRH2 | |
| SCHEMBL8540076 | 0.78 | DRD3 (0.53) | DRD3DRD2HRH1KCNH2HRH2 | |
| SCHEMBL9423729 | 0.75 | DRD3 (0.53) | DRD3DRD2HRH1KCNH2HRH2 | |
| SCHEMBL8537432 | 0.73 | HRH1 (0.57) | DRD3DRD2HRH1KCNH2HRH2 | |
| SCHEMBL7670965 | 0.72 | DRD3 (0.72) | DRD3DRD2HRH1KCNH2HRH2 | |
| SCHEMBL8536653 | 0.72 | DRD3 (0.50) | DRD3DRD2HRH1KCNH2HRH2 | |
| SCHEMBL8540079 | 0.71 | DRD3 (0.53) | DRD3DRD2HRH1KCNH2HRH2 | |
| SCHEMBL16769339 | 0.70 | DRD3 (0.67) | DRD3DRD2HRH1KCNH2HRH2 | |
| SCHEMBL16769338 | 0.70 | DRD3 (0.67) | DRD3DRD2HRH1KCNH2HRH2 | |
| Hydrochloric Acid SCHEMBL10503557 | 0.70 | DRD3 (0.69) | DRD3DRD2HRH1KCNH2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | claimed |
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | disclosed |