Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | GHSR | Q92847 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 9/20 | 0.49 |
| ▸ | DRD2 | P14416 | 8/20 | 0.49 |
| ▸ | HRH2 | P25021 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540076 | 0.88 | DRD3 (0.53) | HRH1KCNH2OPRK1LMNAADORA3 | |
| SCHEMBL9423729 | 0.84 | DRD3 (0.53) | HRH1KCNH2OPRK1LMNAADORA3 | |
| SCHEMBL8537572 | 0.83 | DRD3 (0.47) | HRH1KCNH2OPRK1LMNAADORA3 | |
| SCHEMBL8536653 | 0.82 | DRD3 (0.50) | HRH1KCNH2OPRK1LMNANR1I2 | |
| SCHEMBL8537793 | 0.81 | P2RX7 (0.53) | DRD3DRD2HTR2A | |
| SCHEMBL8539201 | 0.81 | HRH1 (0.54) | HRH1KCNH2OPRK1LMNANR1I2 | |
| SCHEMBL7283745 | 0.75 | DRD3 (0.50) | HRH1KCNH2OPRK1DRD3DRD2 | |
| SCHEMBL7670965 | 0.75 | DRD3 (0.72) | HRH1KCNH2OPRK1LMNADRD3 | |
| SCHEMBL8541391 | 0.73 | ACHE (0.49) | DRD3DRD2HTR2ADRD4HTR7 | |
| SCHEMBL9702546 | 0.73 | DRD3 (0.47) | HRH1KCNH2OPRK1LMNAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508334-B1 | Novel aminophenol derivatives and pharmaceutical compositions thereof | GREEN CROSS CORP (JP) | 1998-01-07 | — | — | EP | claimed |
| US-5308840-A | Antioxidants, antiallergens and antiinflammatory agents | GREEN CROSS CORPORATION (JP) | 1994-05-03 | — | — | US | claimed |
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | claimed |
| EP-0508334-B1 | Novel aminophenol derivatives and pharmaceutical compositions thereof | GREEN CROSS CORP (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5308840-A | Antioxidants, antiallergens and antiinflammatory agents | GREEN CROSS CORPORATION (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | disclosed |