Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.53 |
| ▸ | DRD2 | P14416 | 9/20 | 0.53 |
| ▸ | USP2 | O75604 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | HRH2 | P25021 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540076 | 0.96 | DRD3 (0.53) | DRD3DRD2USP2KCNH2HRH1 | |
| SCHEMBL8537572 | 0.92 | DRD3 (0.47) | DRD3DRD2USP2KCNH2HRH1 | |
| SCHEMBL8537793 | 0.91 | P2RX7 (0.53) | DRD3DRD2HTR2A | |
| SCHEMBL8537432 | 0.84 | HRH1 (0.57) | DRD3DRD2USP2KCNH2HRH1 | |
| SCHEMBL8541391 | 0.83 | ACHE (0.49) | DRD3DRD2ADRA1AHTR2ACHRM1 | |
| SCHEMBL8536653 | 0.81 | DRD3 (0.50) | DRD3DRD2USP2KCNH2HRH1 | |
| SCHEMBL8536534 | 0.79 | BCHE (0.53) | DRD3DRD2KCNH2HRH1CYP3A4 | |
| SCHEMBL8537394 | 0.77 | DRD3 (0.51) | DRD3DRD2USP2KCNH2HRH1 | |
| SCHEMBL12223670 | 0.77 | HRH3 (0.68) | MEN1KMT2A | |
| SCHEMBL9702546 | 0.75 | DRD3 (0.47) | DRD3DRD2USP2KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308840-A | Antioxidants, antiallergens and antiinflammatory agents | GREEN CROSS CORPORATION (JP) | 1994-05-03 | — | — | US | claimed |