Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | BAX | Q07812 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845542 | 0.87 | LTA4H (0.40) | BCL2MCL1LTA4HTSHRPTGS1 | |
| SCHEMBL9368279 | 0.84 | BCL2 (0.41) | BCL2MCL1LTA4HTSHRPTGS1 | |
| SCHEMBL8845356 | 0.84 | BCL2 (0.41) | BCL2MCL1LTA4HTSHRPTGS1 | |
| SCHEMBL2764978 | 0.80 | BCL2 (0.35) | BCL2MCL1LTA4HTSHRPTGS1 | |
| SCHEMBL28272264 | 0.74 | ESR1 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL185135 | 0.74 | GABRA1 (0.43) | TSHRPTGS1HPGDKMT2A | |
| SCHEMBL5076801 | 0.73 | BCL2 (0.57) | BCL2MCL1LTA4HTSHRPTGS1 | |
| SCHEMBL4360185 | 0.73 | MEN1 (0.47) | BCL2MCL1LTA4HTSHRPTGS1 | |
| SCHEMBL471866 | 0.72 | GABRA1 (0.41) | — | |
| SCHEMBL28270623 | 0.72 | TAAR1 (0.39) | TSHRCYP2D6MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481921-A1 | Substituted carbodiimides and thio-ureas and their utilisation against insects | CIBA-GEIGY AG (CH) | 1992-04-22 | — | — | EP | disclosed |