Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.36 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL4085700 | 0.78 | PI4KA (0.58) | SMN1; SMN2LMNACDK1HIF1AHSPA5 | |
| Ribose (Furanose) SCHEMBL4079014 | 0.78 | PI4KA (0.58) | SMN1; SMN2LMNACDK1HIF1AHSPA5 | |
| Ribose (Furanose) SCHEMBL8324675 | 0.78 | ADA (0.41) | ADASMN1; SMN2LMNAALDH1A1POLB | |
| Ribose (Furanose) SCHEMBL4391869 | 0.77 | ADA (0.47) | ADASMN1; SMN2LMNAALDH1A1POLB | |
| Ribose (Furanose) SCHEMBL11213314 | 0.75 | TP53 (0.39) | SMN1; SMN2ALDH1A1HIF1AHSPA5HSPA8 | |
| Ribose (Furanose) SCHEMBL4391872 | 0.74 | ADA (0.41) | ADASMN1; SMN2LMNACDK1CDK4 | |
| Ribose (Furanose) SCHEMBL5199714 | 0.74 | ADA (0.41) | ADASMN1; SMN2LMNACDK1CDK4 | |
| Ribose (Furanose) SCHEMBL27484456 | 0.74 | ADA (0.41) | ADASMN1; SMN2LMNACDK1CDK4 | |
| Hydrochloric Acid SCHEMBL310498 | 0.73 | RET (0.43) | ALDH1A1HIF1AHTTRAB9A | |
| Hydrochloric Acid SCHEMBL311528 | 0.73 | RET (0.43) | ALDH1A1HIF1AHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012718-A1 | ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1992-08-06 | — | — | WO | claimed |