Ribose (Furanose)

Ribose (Furanose)

SCHEMBL5199714

OC[C@H]1OC(O)[C@@H](O)[C@@H]1O.c1ncc2[nH]cnc2n1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ADA P00813 1/20 0.41
PNP P00491 1/20 0.37
ADK P55263 1/20 0.36
HIF1A Q16665 1/20 0.36
CDK1 P06493 1/20 0.34
CDK4 P11802 1/20 0.34
CCNB1 P14635 1/20 0.34
CCND1 P24385 1/20 0.34
MAPT P10636 2/20 0.34
CDA P32320 1/20 0.34
PYGL P06737 3/20 0.34
ATM Q13315 1/20 0.34
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ribose (Furanose) SCHEMBL4391872 1.00 ADA (0.41) ADAPNPADKHIF1ACDK1
Ribose (Furanose) SCHEMBL27484456 1.00 ADA (0.41) ADAPNPADKHIF1ACDK1
Glucosamine SCHEMBL28890688 0.91 PYGL (0.38) ADAPNPADKHIF1ACDK1
Purine SCHEMBL11573661 0.82 P2RX3 (0.45) SMN1; SMN2
Purine SCHEMBL4378871 0.81 TREH (0.33) ADA
2-Aminopurine SCHEMBL28775710 0.79 ALDH1A1 (0.59) PNPADKHIF1APYGLKDM4E
Purine SCHEMBL6426435 0.79 ADORA2A (0.35) ADALMNA
Ribose (Furanose) SCHEMBL4391869 0.78 ADA (0.47) ADAPNPADKHIF1ACDK1
Purine SCHEMBL27770115 0.77 CYP3A4 (0.40) HIF1AKDM4ELMNA
Purine SCHEMBL28264029 0.77 ALDH1A1 (0.45) KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6548486-B1 New viricide compounds of the general formula: Nu-O-Fa, wherein O represents an oxygen, Nu is a nucleoside or nucleoside analogue, and Fa is an acyl group of mono-unsaturated c18-c20 fatty acid NORSK HYDRO A.S. (NO) 2003-04-15 US claimed
JP-2873313-B2 1999-03-24 JP claimed
EP-0642525-B1 Nucleosides being O-acylated with a mono-unsaturated omega-9 C18 or C20 fatty acid NORSK HYDRO AS (NO) 1997-05-02 EP claimed
EP-0642525-A1 CHEMICAL COMPOUNDS. NORSK HYDRO AS (NO) 1995-03-15 EP claimed
WO-1993007163-A1 CHEMICAL COMPOUNDS NORSK HYDRO A.S. (NO) 1993-04-15 WO claimed
US-4371613-A TRANSARABINOSYLATION USING AN ENZYME FROM BACTERIA, AN ARABINOSE DONOR AND A PURINE SOURCE AJINOMOTO COMPANY INCORPORATED (JP) 1983-02-01 US claimed
JP-56008696-A None JP disclosed
JP-56008695-A None JP disclosed
JP-56008695-A None JP disclosed
JP-55015716-A None JP disclosed
JP-55015716-A None JP disclosed
JP-55013010-A None JP disclosed
JP-55013010-A None JP disclosed
JP-S05537167-A 0001-01-01 JP disclosed
JP-S05515716-A 0001-01-01 JP disclosed
JP-S05513010-A 0001-01-01 JP disclosed
JP-S05537166-A 0001-01-01 JP disclosed
JP-S05537166-A 0001-01-01 JP disclosed
JP-S05537167-A 0001-01-01 JP disclosed
JP-S05513010-A 0001-01-01 JP disclosed