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Ribose (Furanose)

Ribose (Furanose)

SCHEMBL4085700

Nc1ncnc2[nH]ncc12.OC[C@H]1OC(O)[C@H](O)[C@@H]1O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PI4KA P42356 2/20 0.58
▸ PI4K2B Q8TCG2 2/20 0.58
▸ PI4K2A Q9BTU6 2/20 0.58
▸ PI4KB Q9UBF8 2/20 0.58
▸ RET P07949 1/20 0.58
▸ XDH P47989 1/20 0.58
▸ LRRK2 Q5S007 1/20 0.58
▸ HIF1A Q16665 2/20 0.45
▸ ADK P55263 6/20 0.45
▸ DOT1L Q8TEK3 2/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ DPP4 P27487 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ SLC28A1 O00337 1/20 0.43
▸ MAP3K7 O43318 1/20 0.43
▸ SLC28A2 O43868 1/20 0.43
▸ GAPDH P04406 1/20 0.43
▸ ADORA3 P0DMS8 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ ADORA2A P29274 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ribose (Furanose) SCHEMBL4079014 1.00 PI4KA (0.58) PI4KAPI4K2BPI4K2API4KBRET
Ribose (Furanose) SCHEMBL11213314 0.83 TP53 (0.39) PI4KAPI4K2BPI4K2API4KBRET
Ribose (Furanose) SCHEMBL8324675 0.82 ADA (0.41) PI4KAPI4K2BPI4K2API4KBHIF1A
Ribose (Furanose) SCHEMBL9702729 0.78 ADA (0.42) HIF1ASMN1; SMN2HSPA5HSPA8RXFP1
Ribose (Furanose) SCHEMBL4083364 0.78 HIF1A (0.47) PI4KAPI4K2BPI4K2API4KBHIF1A
SCHEMBL11327749 0.77 SLC5A2 (0.43) —
Allopurinol SCHEMBL1144826 0.77 SMN1; SMN2 (0.60) XDHSMN1; SMN2MEN1ADORA2AKMT2A
SCHEMBL11363 0.76 XDH (1.00) PI4KAPI4K2BPI4K2API4KBRET
SCHEMBL29351045 0.76 XDH (1.00) PI4KAPI4K2BPI4K2API4KBRET
SCHEMBL9346485 0.75 ADK (0.42) PI4KAPI4K2BPI4K2API4KBRET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7491818-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2009-02-17 — — US disclosed
US-7423143-B2 Nucleic acid labeling compounds AFFYMETRIX. INC. (US) 2008-09-09 — — US disclosed
US-7291463-B2 Incubating/condensating pseudoisocytidine molecule with (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to provide a pseudouridine molecule; oncology diagnosis AFFYMETRIX, INC. (US) 2007-11-06 — — US disclosed
US-7282327-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2007-10-16 — — US disclosed
US-7179905-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2007-02-20 — — US disclosed
US-20050287563-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2005-12-29 — — US disclosed
US-6965020-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2005-11-15 — — US disclosed
EP-1589025-A2 Nucleic acid labeling compounds Affymetrix, Inc. (US) 2005-10-26 — — EP disclosed
US-20050164268-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2005-07-28 — — US disclosed
EP-1124838-B1 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX INC (US) 2005-06-01 — — EP disclosed
US-20040210045-A1 Nucleic acid labeling compounds MCGALL GLENN (US) 2004-10-21 — — US disclosed
US-20040101892-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2004-05-27 — — US disclosed
US-20040002595-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2004-01-01 — — US disclosed
US-20030180757-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2003-09-25 — — US disclosed
US-6596856-B2 For probes, comprising a heterocycle condensed with a cyclic group such as ribofuranose derivative; biotin and 5-carboxyfluorescein derivatives AFFYMETRIX, INC. 2003-07-22 — — US disclosed
US-20020165372-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2002-11-07 — — US disclosed
US-20010044531-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2001-11-22 — — US disclosed
US-20010018514-A1 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX, INC. 2001-08-30 — — US disclosed
EP-1124838-A2 NUCLEIC ACID LABELING COMPOUNDS Affymetrix, Inc. (US) 2001-08-22 — — EP disclosed
WO-2000006771-A2 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX, INC. (US) 2000-02-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002595-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL PI4KA 4122/4885PI4K2B 4478/4885PI4K2A 4436/4885
US-20030180757-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL PI4KA 4122/4885PI4K2B 4478/4885PI4K2A 4436/4885
US-20050164268-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL PI4KA 4122/4885PI4K2B 4478/4885PI4K2A 4436/4885
US-20040101892-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL PI4KA 4122/4885PI4K2B 4478/4885PI4K2A 4436/4885
US-20010044531-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL PI4KA 4122/4885PI4K2B 4478/4885PI4K2A 4436/4885
US-20050287563-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL PI4KA 4122/4885PI4K2B 4478/4885PI4K2A 4436/4885
US-20010018514-A1 NUCLEIC ACID LABELING COMPOUNDS RNGTT, DUT, FBL PI4KA 4122/4885PI4K2B 4478/4885PI4K2A 4436/4885
US-20020165372-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL PI4KA 4122/4885PI4K2B 4478/4885PI4K2A 4436/4885
US-20040210045-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL PI4KA 4122/4885PI4K2B 4478/4885PI4K2A 4436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.