Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.67 |
| ▸ | IGF1R | P08069 | 1/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | BLM | P54132 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702060 | 0.89 | MAPT (0.58) | INSRIGF1RFFAR1MAPTMEN1 | |
| SCHEMBL20036943 | 0.85 | INSR (0.75) | INSRIGF1RFFAR1ALDH1A1RAB9A | |
| SCHEMBL29606754 | 0.85 | FFAR1 (0.67) | INSRIGF1RFFAR1MAPTMEN1 | |
| SCHEMBL9093298 | 0.85 | FFAR1 (0.67) | INSRIGF1RFFAR1MAPTMEN1 | |
| SCHEMBL28392967 | 0.83 | HTT (0.62) | INSRIGF1RFFAR1MAPTMEN1 | |
| SCHEMBL27527525 | 0.83 | FFAR1 (0.60) | INSRIGF1RFFAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6419281 | 0.81 | FFAR1 (0.58) | INSRIGF1RFFAR1MEN1KMT2A | |
| SCHEMBL9702101 | 0.81 | MAPT (0.57) | FFAR1MAPTMEN1BLMKMT2A | |
| SCHEMBL4149226 | 0.80 | INSR (0.49) | INSRIGF1RFFAR1MAPTMEN1 | |
| SCHEMBL31060190 | 0.80 | INSR (1.00) | INSRIGF1RFFAR1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221677-B1 | P-AMINOPHENOLS, DERIVATIVES THEREOF AND USE FOR MANUFACTURE OF A MEDICAMENT | E.R. Squibb & Sons, Inc. (US) | 1992-09-09 | — | — | EP | claimed |
| US-4910208-A | Skin disorders, antiinflammatory agent | E. R. SQUIBB & SONS, INC. (US) | 1990-03-20 | — | — | US | claimed |
| EP-0221677-A2 | p-Aminophenols, derivatives thereof and use for manufacture of a medicament | E.R. Squibb & Sons, Inc. (US) | 1987-05-13 | — | — | EP | claimed |