Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703148 | 0.93 | MEN1 (0.45) | MEN1KMT2AATMKDM4ERAB9A | |
| SCHEMBL9703146 | 0.90 | RAB9A (0.46) | MEN1KMT2AATMKDM4ERAB9A | |
| SCHEMBL9702375 | 0.89 | KDM4E (0.54) | MEN1KMT2AAKT1KDM4ERAB9A | |
| SCHEMBL9703126 | 0.87 | KDM4E (0.51) | MEN1KMT2AAKT1KDM4ERAB9A | |
| SCHEMBL9702831 | 0.86 | RAB9A (0.50) | MEN1KMT2AAKT1KDM4ERAB9A | |
| SCHEMBL9704095 | 0.85 | ALDH1A1 (0.50) | MEN1KMT2AAKT1KDM4ERAB9A | |
| SCHEMBL9702960 | 0.83 | KDM4E (0.55) | MEN1KMT2AAKT1KDM4ERAB9A | |
| SCHEMBL9704935 | 0.81 | KDM4E (0.56) | MEN1KMT2AAKT1KDM4ERAB9A | |
| SCHEMBL9702712 | 0.81 | KDM4E (0.56) | MEN1KMT2AAKT1KDM4ERAB9A | |
| SCHEMBL19793302 | 0.81 | POLB (0.46) | MEN1KMT2AATMKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143642-A | Thiadiazoles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |