Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17967210 | 0.82 | ALDH1A1 (0.45) | RAB9AALDH1A1KMT2AMEN1ATM | |
| SCHEMBL9702795 | 0.81 | MEN1 (0.43) | RAB9AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL17967124 | 0.79 | ALDH1A1 (0.72) | POLBALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9702375 | 0.77 | KDM4E (0.54) | RAB9AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL17967254 | 0.76 | TDP1 (0.45) | POLBRAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL19793301 | 0.75 | ALDH1A1 (0.45) | POLBALDH1A1KMT2AMEN1ATM | |
| SCHEMBL17967187 | 0.74 | KDM4E (0.48) | RAB9AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL17967116 | 0.73 | FFAR1 (0.52) | RAB9ASRCENPP2 | |
| SCHEMBL9703148 | 0.73 | MEN1 (0.45) | RAB9AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL17967149 | 0.72 | FFAR1 (0.48) | ALDH1A1KMT2AMEN1LMNASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022742-A1 | AUTOTAXIN INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022742-A1 | AUTOTAXIN INHIBITORS | ENPP2, RNASE1, ATXN10 | POLB 1170/4885RAB9A 810/4885ALDH1A1 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.