Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703576 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAGPR174TDP1POLB | |
| SCHEMBL9702877 | 0.78 | ALDH1A1 (0.38) | ALDH1A1LMNAGPR174TDP1KDM4E | |
| SCHEMBL15522549 | 0.68 | KMT2A (0.55) | ALDH1A1LMNAGPR174POLBHTT | |
| SCHEMBL11025540 | 0.67 | MAOB (0.46) | ALDH1A1TDP1POLBAPEX1HTT | |
| SCHEMBL8084718 | 0.66 | SMN1; SMN2 (0.46) | ALDH1A1LMNATDP1KDM4EKMT2A | |
| SCHEMBL7913532 | 0.66 | SMN1; SMN2 (0.46) | ALDH1A1LMNAHTTKDM4EKMT2A | |
| SCHEMBL11026108 | 0.65 | TDP1 (0.42) | ALDH1A1TDP1POLBAPEX1HTT | |
| SCHEMBL11219249 | 0.64 | TSHR (0.67) | ALDH1A1TDP1POLBAPEX1HTT | |
| SCHEMBL11230384 | 0.64 | TSHR (0.67) | ALDH1A1TDP1POLBAPEX1HTT | |
| SCHEMBL14907540 | 0.64 | TSHR (0.67) | ALDH1A1TDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155793-A | OPTICAL COMPONENT FOR APPLICATIONS IN INTEGRATED OPTICS | THOMSON-CSF (FR) | 1992-10-13 | — | — | US | disclosed |
| EP-0442796-A1 | Optical component for applications in integrated optics | THOMSON-CSF (FR) | 1991-08-21 | — | — | EP | disclosed |