Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703576 | 0.84 | ALDH1A1 (0.41) | ALDH1A1LMNAGPR174KMT2AMCOLN3 | |
| SCHEMBL9702869 | 0.78 | ALDH1A1 (0.35) | ALDH1A1LMNAGPR174KMT2AKDM4E | |
| SCHEMBL15522549 | 0.69 | KMT2A (0.55) | ALDH1A1LMNAGPR174KMT2AMAPT | |
| SCHEMBL15294334 | 0.66 | KMT2A (0.39) | ALDH1A1KMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL15294347 | 0.66 | KMT2A (0.39) | ALDH1A1KMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL8084718 | 0.65 | SMN1; SMN2 (0.46) | ALDH1A1LMNAKMT2AMAPTKDM4E | |
| SCHEMBL15294369 | 0.65 | MAPT (0.38) | ALDH1A1KMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL7913532 | 0.65 | SMN1; SMN2 (0.46) | ALDH1A1LMNAKMT2AMAPTKDM4E | |
| SCHEMBL29512633 | 0.64 | MAPT (0.59) | ALDH1A1GPR174KMT2AMAPTCYP1A2 | |
| SCHEMBL29512894 | 0.64 | CUL4A (0.49) | ALDH1A1LMNAKMT2AMCOLN3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155793-A | OPTICAL COMPONENT FOR APPLICATIONS IN INTEGRATED OPTICS | THOMSON-CSF (FR) | 1992-10-13 | — | — | US | disclosed |
| EP-0442796-A1 | Optical component for applications in integrated optics | THOMSON-CSF (FR) | 1991-08-21 | — | — | EP | disclosed |