Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534377 | 0.89 | USP2 (0.36) | USP2TSHRGAA | |
| SCHEMBL794227 | 0.82 | USP2 (0.34) | USP2TSHR | |
| SCHEMBL28398512 | 0.81 | TGFBR1 (0.39) | USP2TSHR | |
| SCHEMBL9700328 | 0.81 | PGR (0.32) | — | |
| Hydrochloric Acid SCHEMBL793324 | 0.80 | USP2 (0.33) | USP2TSHR | |
| SCHEMBL902118 | 0.79 | ALDH1A1 (0.36) | USP2TSHR | |
| SCHEMBL34096 | 0.79 | TGFBR1 (0.44) | USP2TSHR | |
| SCHEMBL14678189 | 0.79 | TGFBR1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL7945240 | 0.78 | TGFBR1 (0.43) | — | |
| Propionic Acid SCHEMBL14676809 | 0.77 | TGFBR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132454-A | Antihypoxic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5066677-A | Antihypoxic agents, treatment of disorders resulting from reduced oxygen supply to brain | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0387074-A2 | Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |