Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616457 | 0.87 | CA2 (0.59) | ALDH1A1TDP1TP53CA2CA12 | |
| SCHEMBL6752842 | 0.79 | CA1 (0.57) | ALDH1A1TDP1TP53CA2CA12 | |
| SCHEMBL11207554 | 0.77 | CA12 (0.63) | ALDH1A1TDP1TP53CA2CA12 | |
| SCHEMBL28901448 | 0.77 | CA12 (0.63) | ALDH1A1TDP1TP53CA2CA12 | |
| SCHEMBL3975244 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TDP1TP53CA2CA12 | |
| SCHEMBL10695596 | 0.76 | CA12 (0.61) | ALDH1A1TDP1TP53CA2CA12 | |
| SCHEMBL7148200 | 0.75 | ALDH1A1 (0.57) | ALDH1A1TDP1TP53CA2CA12 | |
| SCHEMBL10404798 | 0.75 | GAA (0.50) | ALDH1A1TDP1TP53CYP3A4GAA | |
| SCHEMBL8768517 | 0.75 | CA12 (0.51) | ALDH1A1TDP1CA2CA12CA9 | |
| SCHEMBL11784083 | 0.75 | CA12 (0.51) | ALDH1A1TDP1TP53CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106718-A | Heat resistant relief structures | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0364949-A2 | Heat-stable positive photoresist | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |