Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9087468 | 0.83 | HSPB1 (0.59) | HSPB1MEN1KMT2ARXFP1LMNA | |
| SCHEMBL347599 | 0.81 | HSPB1 (0.53) | HSPB1MEN1KMT2ARXFP1LMNA | |
| SCHEMBL9703810 | 0.77 | HSPB1 (0.48) | HSPB1MEN1KMT2ARXFP1LMNA | |
| SCHEMBL11407398 | 0.75 | HSPB1 (0.55) | HSPB1MEN1KMT2ALMNARAB9A | |
| SCHEMBL7632959 | 0.75 | HSPB1 (0.66) | HSPB1MEN1KMT2ARXFP1LMNA | |
| SCHEMBL8444172 | 0.75 | NCOA1 (0.58) | HSPB1MEN1KMT2ALMNARAB9A | |
| SCHEMBL30570728 | 0.74 | HSPB1 (0.57) | HSPB1MEN1KMT2ARXFP1LMNA | |
| SCHEMBL9330033 | 0.74 | HSPB1 (0.57) | HSPB1MEN1KMT2ARXFP1LMNA | |
| SCHEMBL9703068 | 0.73 | ALDH1A1 (0.44) | LMNARAB9AHTTALDH1A1MAPT | |
| SCHEMBL11816088 | 0.73 | PDE7A (0.48) | HSPB1MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012120-A1 | BIS(AMINOPHENOXY)NAPHTHALENES AND BIS(NITROPHENOXY)NAPHTHALENES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-23 | — | — | WO | disclosed |