SCHEMBL347599

SCHEMBL347599

O=[N+]([O-])c1ccc(Oc2cccc3ccccc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPB1 P04792 3/20 0.53
ALOX5 P09917 2/20 0.52
PTGES O14684 1/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
RXFP1 Q9HBX9 1/20 0.50
LMNA P02545 5/20 0.49
MAPT P10636 4/20 0.49
HTT P42858 3/20 0.49
RECQL P46063 1/20 0.49
PIN1 Q13526 1/20 0.49
ALDH1A1 P00352 3/20 0.49
RAB9A P51151 1/20 0.48
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
GAA P10253 1/20 0.46
CYP2C19 P33261 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MITF O75030 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8999469 0.86 ALDH1A1 (0.56) HSPB1ALOX5PTGESMEN1KMT2A
SCHEMBL28053128 0.84 ALOX5 (0.59) ALOX5PTGESMEN1KMT2ALMNA
SCHEMBL7632959 0.84 HSPB1 (0.66) HSPB1MEN1KMT2ARXFP1LMNA
SCHEMBL14567939 0.84 KMT2A (0.60) MEN1KMT2ALMNAMAPTHTT
SCHEMBL9703810 0.83 HSPB1 (0.48) HSPB1ALOX5PTGESMEN1KMT2A
SCHEMBL30570728 0.83 HSPB1 (0.57) HSPB1MEN1KMT2ARXFP1LMNA
SCHEMBL9330033 0.83 HSPB1 (0.57) HSPB1MEN1KMT2ARXFP1LMNA
SCHEMBL2078871 0.82 L3MBTL1 (0.54) MEN1KMT2ALMNAMAPTHTT
SCHEMBL11721323 0.81 HSPB1 (0.54) HSPB1MEN1KMT2ARXFP1LMNA
SCHEMBL18476534 0.81 ALOX5 (0.47) HSPB1ALOX5PTGESMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084056-A1 SUBSTITUTED OXOISOINDOLINYL PIPERIDINE-2,6-DIONE COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-03-13 US disclosed
CN-116779958-A Flame-retardant gel polymer electrolyte and application thereof in lithium-sulfur secondary battery 上海交通大学 2023-09-19 CN disclosed
CN-114656399-A Cavity spirochete imine silver complex 南京工业大学 2022-06-24 CN disclosed
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-8048982-B2 Method for producing aromatic compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-01 US disclosed
CN-101001900-B Process for producing aromatic compound polymer SUMITOMO CHEMICAL CO 2011-04-20 CN disclosed
CN-101914111-A The preparation method of aromatic compound polymer SUMITOMO CHEMICAL CO 2010-12-15 CN disclosed
EP-2241548-A1 Vanadium di-nuclear complex Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-2241547-A1 Method for producing aromatic compound polymer Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
US-20090018309-A1 Method for Producing Aromatic Compound Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
EP-0966436-A1 ARYL SULFONAMIDES AND ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Bayer Aktiengesellschaft (DE) 1999-12-29 EP disclosed
WO-1998037061-A1 ARYL SULFONAMIDES AND ANALOGUES THEREOF AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES BAYER AKTIENGESELLSCHAFT (DE) 1998-08-27 WO disclosed
EP-0081743-B1 NAPHTHOXYPHENYL UREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1986-05-14 EP disclosed
EP-0050321-B1 NOVEL BICYCLOOXYPHENYL UREAS, PROCESS FOR THEIR PREPARATION AND PESTICIDES CONTAINING THEM UNION CARBIDE CORPORATION (US) 1985-08-21 EP disclosed
US-4426385-A Insecticidal bicyclooxyphenyl ureas UNION CARBIDE CORPORATION (US) 1984-01-17 US disclosed
EP-0081743-A2 Naphthoxyphenyl ureas, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1983-06-22 EP disclosed
EP-0013414-B1 UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES CELAMERCK GmbH & Co. KG (DE) 1982-06-23 EP disclosed
EP-0050321-A2 Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them UNION CARBIDE CORPORATION (US) 1982-04-28 EP disclosed
US-4275077-A Insecticidal acyl urea derivatives CELAMERCK GMBH & CO. KG (DE) 1981-06-23 US disclosed
EP-0013414-A2 Urea derivatives, process for their preparation and their use as insecticides CELAMERCK GmbH & Co. KG (DE) 1980-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084056-A1 SUBSTITUTED OXOISOINDOLINYL PIPERIDINE-2,6-DIONE COMPOUNDS CCNA1, CCNI, CCNE1 HSPB1 2029/4885ALOX5 1864/4885PTGES 368/4885
US-20090018309-A1 Method for Producing Aromatic Compound Polymer PAH, MAOA, AHR HSPB1 2032/4885ALOX5 410/4885PTGES 535/4885
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER PAH, MAOA, AHR HSPB1 1924/4885ALOX5 418/4885PTGES 524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.