Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 6/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703788 | 0.90 | KDM4E (0.64) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9703328 | 0.89 | KDM4E (0.68) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9705497 | 0.88 | KDM4E (0.45) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2876259 | 0.88 | AADAT (0.69) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10999003 | 0.88 | LMNA (0.65) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9703769 | 0.87 | KDM4E (0.68) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9703760 | 0.87 | LMNA (0.49) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9704650 | 0.87 | KDM4E (0.43) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| Iodide SCHEMBL11169703 | 0.87 | LMNA (0.64) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9703653 | 0.87 | KDM4E (0.51) | LMNAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203795-B1 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4720495-A | Benzo[ij]quinolizine-2-carboxylic acids useful for treating bacterial infection | TOKYO TANABE CO. LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0203795-A2 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |