Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.68 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | TUBB | P07437 | 1/20 | 0.67 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.67 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.67 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.67 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.67 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.67 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.67 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.67 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.67 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.67 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.67 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9703769 | 0.98 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL2876259 | 0.91 | AADAT (0.69) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9705571 | 0.90 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9705609 | 0.90 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10401667 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9705503 | 0.89 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9703832 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9703124 | 0.89 | LMNA (0.55) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9703601 | 0.88 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9703884 | 0.88 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203795-B1 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | claimed |
| US-4946844-A | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE CO., LTD. (JP) | 1990-08-07 | — | — | US | claimed |
| EP-0323189-A2 | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE COMPANY LIMITED (JP) | 1989-07-05 | — | — | EP | claimed |
| US-4720495-A | Benzo[ij]quinolizine-2-carboxylic acids useful for treating bacterial infection | TOKYO TANABE CO. LIMITED (JP) | 1988-01-19 | — | — | US | claimed |
| EP-0203795-A2 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1986-12-03 | — | — | EP | claimed |
| JP-1287027-A | — | — | None | — | — | JP | disclosed |
| JP-1250380-A | — | — | None | — | — | JP | disclosed |
| EP-0203795-B1 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-4946844-A | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| JP-H01287027-A | INJECTION CONTAINING 9-FLUORO-6,7-DIHYDRO-5-METHYL-8-(4-METHYL-1-PIPERAZINYL)-1,-7-DIOXO-1H,5H-BENZO(IJ)QUINOLIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE MONOHYDRATE | TOKYO TANABE CO LTD | 1989-11-17 | — | — | JP | disclosed |
| JP-H01250380-A | OPTICALLY ACTIVE BENZOQUINOLIZINE DERIVATIVE, ITS PRODUCTION AND ANTIBACTERIAL AGENT CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | TOKYO TANABE CO LTD | 1989-10-05 | — | — | JP | disclosed |
| EP-0323189-A2 | Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient | TOKYO TANABE COMPANY LIMITED (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4720495-A | Benzo[ij]quinolizine-2-carboxylic acids useful for treating bacterial infection | TOKYO TANABE CO. LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0203795-A2 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |