Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473100 | 0.91 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6820422 | 0.83 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL19732753 | 0.82 | CRHR1 (0.46) | ALDH1A1MEN1KMT2ALMNACRHR1 | |
| SCHEMBL380689 | 0.80 | KMT2A (0.45) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29788888 | 0.77 | PIM1 (0.36) | ALDH1A1MEN1KMT2ALMNATRPA1 | |
| SCHEMBL11053986 | 0.77 | MAPT (0.42) | MAPTALDH1A1TSHRTP53EGFR | |
| SCHEMBL4300630 | 0.77 | TRPA1 (0.39) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28279552 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPK1TP53CRHR1 | |
| SCHEMBL28278211 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPK1TP53CRHR1 | |
| Hydrochloric Acid SCHEMBL10630985 | 0.75 | ALDH1A1 (0.38) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215200-B1 | USE OF SULFANILAMIDO QUINOXALINES IN THE TREATMENT OF NEOPLASTIC DISEASES | MERCK & CO. INC. (US) | 1992-09-09 | — | — | EP | disclosed |