SCHEMBL9703470

SCHEMBL9703470

CCOC(=O)/C(=N/OC1CC1)C(C)=O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.40
MAPT P10636 3/20 0.37
ALDH1A1 P00352 5/20 0.35
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TSHR P16473 1/20 0.35
GAA P10253 2/20 0.34
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
ABCB1 P08183 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
EGLN1 Q9GZT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9703474 1.00 GLO1 (0.40) GLO1MAPTALDH1A1LMNAHSD17B10
SCHEMBL10832578 0.95 GLO1 (0.37) GLO1MAPTALDH1A1LMNAHSD17B10
SCHEMBL10832581 0.95 GLO1 (0.37) GLO1MAPTALDH1A1LMNAHSD17B10
SCHEMBL10419049 0.94 GLO1 (0.36) GLO1MAPTALDH1A1LMNAHSD17B10
SCHEMBL10419048 0.94 GLO1 (0.36) GLO1MAPTALDH1A1LMNAHSD17B10
SCHEMBL9703423 0.86 ALDH1A1 (0.37) GLO1MAPTALDH1A1TSHRGAA
SCHEMBL9703426 0.86 ALDH1A1 (0.37) GLO1MAPTALDH1A1TSHRGAA
SCHEMBL9703590 0.84 ALOX15 (0.38) GLO1MAPTALDH1A1GAANOS3
SCHEMBL9703594 0.84 ALOX15 (0.38) GLO1MAPTALDH1A1GAANOS3
SCHEMBL9703800 0.83 GLO1 (0.36) GLO1MAPTALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192210-B1 CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-10-21 EP disclosed
US-4973699-A Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-11-27 US disclosed
US-4861769-A Cephem compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-08-29 US disclosed
EP-0192210-A2 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-08-27 EP disclosed