Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.40 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703450 | 0.82 | GAA (0.43) | GAATSHRGRIN2DGRIN3BLMNA | |
| SCHEMBL9703948 | 0.71 | ATM (0.37) | GAATSHRGRIN2DGRIN3BLMNA | |
| SCHEMBL2478229 | 0.68 | GAA (0.61) | GAATSHRLMNAHTR2AHTR2C | |
| SCHEMBL20677871 | 0.68 | GAA (0.66) | GAATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL28911160 | 0.67 | GRIN2D (0.47) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL8460563 | 0.67 | TSHR (0.60) | GAATSHRLMNATP53NPC1 | |
| SCHEMBL9704210 | 0.67 | PGK1 (0.36) | GAATSHRGRIN2DGRIN3BLMNA | |
| SCHEMBL29200011 | 0.66 | GAA (0.67) | GAATSHRTP53PTGDRPTGDR2 | |
| SCHEMBL8168167 | 0.66 | TSHR (0.68) | GAATSHRTP53LIG1KDM4E | |
| SCHEMBL30826232 | 0.65 | HTR2C (0.51) | GAATSHRLMNAHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |